pjmccoy1 asked 3 years ago

I recently saw your interview on the Betrayal series.  I have an autoimmune disease, in addition to depression and insomnia.  I am interested in the benefits and use of L-tyrosine and 5htp for depression and anxiety.  I am currently on Bupropion 150mg SR and want to get off it.  I also battle restless legs syndrome, thus why I’m interested in the dopamine effects of L-tyrosine.  Do you know if l-tyrosine can cause augmentation of restless legs syndrome similar to carbidopa/levadopa?  The added advantage of Bupropion for depression is it is RLS friends (doesn’t exacerbate the condition and in fact might help relief restless legs).

1 Answers
Hyla Cass, MD Staff answered 3 years ago

You really have several questions here:
1. Can I take tyrosine (eg my FOCUS formula) with Restless legs syndrome?
Answer: Yes, should not interfere and may even help.
2. Treating Restless legs syndrome: I see it as a mineral deficiency and often stepping up your mineral intake will help— magnesium, potassium, calcium, and also check your iron and ferritin levels and take iron if needed.
3. Getting off bupropion, an antidepressant: You are right to be taking tyrosine — or FOCUS with tyrosine, D,L Phenylalanine, and other synergistic ingredients, plus 5 HTP (taken at least 2 hours away from the drug to avoid serotonin overload or “serotonin syndrome.” As you gradually lower the bupropion with your doctor’s help you can increase the others Also add in Twice Daily Multi to get the remaining cofactors needed to make your neurotransmitters.

Let me know how you do!

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